Bioglutide
Also known as: NA-931
Primary use: Weight loss and muscle preservation
What is Bioglutide?
Bioglutide, also known as NA-931, is a first-in-class oral quadruple receptor agonist developed by Biomed Industries. It targets IGF-1, GLP-1, GIP, and glucagon receptors, demonstrating high oral bioavailability and blood-brain barrier penetration. Currently in Phase 2b/3 trials for obesity and type 2 diabetes, it aids significant weight reduction while preserving muscle mass. Notable concerns include the investigational status and potential GI side effects.
- Promotes weight loss
- Preserves muscle mass
- Reduces visceral fat
Bioglutide simultaneously activates IGF-1, GLP-1, GIP, and glucagon receptors. IGF-1 promotes muscle preservation and insulin sensitivity, while GLP-1 aids appetite suppression and insulin secretion. GIP enhances glucose metabolism and affects fat storage, whereas glucagon increases energy expenditure and fat oxidation.
Safety Tips
- 1DON'T use if you have a personal or family history of medullary thyroid carcinoma.
- 2DON'T stack with other GLP-1 agonists.
- 3DON'T exceed 150mg daily without medical guidance.
- 4AVOID using from unverified sources without analytical testing.
- 5NEVER use if you suspect moisture damage or discoloration.
Who Should NOT Use
- Personal/family history of medullary thyroid carcinoma
Dosage & Protocols
Different purposes have different protocols, dosing, and considerations
Obesity and weight management
moderate evidenceBioglutide is being studied for its potential to aid in substantial weight loss while preserving muscle mass, primarily targeted at obese adults.
Evidence: Phase 2 clinical trials demonstrate significant weight loss and muscle preservation without serious adverse events.
The following are ranges reported in published literature and community discussions. These are NOT recommendations or medical advice.
📋Community-Reported Protocols
The following protocols are compiled from online communities and published literature. Pepbase does not endorse, recommend, or verify these protocols. They are provided for informational purposes only. Individual responses vary significantly. Consult a licensed medical professional before any use.
| Reported Goal | Reported Dose | Reported Frequency | Reported Route |
|---|---|---|---|
| Weight loss | 50mg | Once daily | Oral |
| Weight loss | 150mg | Once daily | Oral |
⏱️Pharmacokinetics
⚡Reported Side Effects
This is not a complete list. Other side effects may occur.
Common
Serious / Rare
- • Pancreatitis symptoms
Injection-Specific Warnings
- None for oral administration
🧊Storage
Harm Reduction Information
Quality Concerns
- Contamination from unregulated sources
- Potential degradation from improper storage
Safety Tips
- Store properly in moisture-protected containers
- Verify supplier credibility with COA and third-party testing
Warning Signs to Stop
- Severe abdominal pain indicating pancreatitis
Seek Medical Help Immediately If
- Persistent abdominal pain
- Any signs of discoloration or degradation in tablets
Frequently Asked Questions
How long until I see effects?
Bioglutide typically starts showing weight loss effects by weeks 1-2, with peak effects around 12 weeks.
What time of day should I take it?
Bioglutide can be taken any time of day, with or without food, as consistent blood levels are maintained.
How can I minimize side effects?
To minimize side effects, start Bioglutide at a lower dose and titrate up as tolerated, monitoring for mild nausea or diarrhea.
Does tolerance develop?
There is no significant evidence of tolerance development with Bioglutide during the short clinical trial periods.
How should I store it?
Store Bioglutide at room temperature or refrigerated, protected from moisture.
Do I need to cycle it?
Bioglutide is typically used in cycles of 12+ weeks as recommended by medical guidance.
Reported Combinations
Compounds reported to be used alongside Bioglutide in community discussions. Not a recommendation.
Ipamorelin
Both promote muscle preservation and fat loss.
BPC-157
Accelerates muscle recovery and enhances healing.
5-Amino-1MQ
Compliments metabolic benefits and weight loss.
Reported Interactions
Interactions reported in literature and community discussions.
Avoid combination due to overlapping mechanisms and increased risk of adverse effects.
Avoid combination due to the risk of compounding side effects.
Avoid combination.
Generally safe to consume alongside Bioglutide.
Safe to take with Bioglutide.
Reconstitution Calculator
100 units = 1 mL
Safety Tips
- Always consult a licensed medical professional for dosing and reconstitution instructions.
- Always double check your units. Mixing up mg and mcg can be very dangerous.
- Make sure to select your syringe type. U-100 and U-50 syringes have different units.
- Ensure you're not adding more BAC than your vial can hold. Most vials have maximum capacities listed.
This calculator is for informational and educational purposes only. It does not provide medical advice, dosing recommendations, or safety determinations. Reference ranges shown are compiled from publicly available sources and are not a substitute for guidance from a licensed healthcare professional.
Legal Status by Region
Regulatory status varies by country. Information provided is for reference only and may change.
USA
investigational
UK
investigational
EU
investigational
Australia
investigational
Canada
investigational
Explore More Research
Browse our database of peptide research information compiled from published literature and community sources.
Other Sources & Citations
Last updated: October 3, 2023