⭐Popular

Omberacetam (Noopept)

Also known as: GVS-111, Noopept, DVD-111, SGS-111

Cognitive
Not FDA Approved

Primary recreational use: Cognitive enhancement

What is Omberacetam (Noopept)?

Omberacetam, also known as Noopept, is a synthetic nootropic dipeptide developed in Russia in 1996 for its potent cognitive-enhancing and neuroprotective properties. It is primarily used to improve memory, learning, and concentration, popular in nootropic communities for cognitive enhancement. While it remains unapproved by the FDA, it is available without a prescription in Russia but banned in some other countries. Users should be cautious of potential neurotoxicity and the lack of long-term safety data.

Primary Benefits

Enhances memory and learning. Improves focus and concentration. Supports neuroplasticity.

How It Works

Omberacetam acts as a prodrug that converts to cycloprolylglycine, which modulates AMPA and NMDA glutamate receptors. It enhances cholinergic neurotransmission and increases BDNF and NGF levels, promoting neuroplasticity and cognitive function. The peptide rapidly crosses the blood-brain barrier, facilitating quick onset of effects.

Safety Tips

Precautions reported in community discussions and literature. This is not a complete list.

  • 1.DON'T exceed the recommended dose of 30mg daily.
  • 2.DON'T use without consulting a healthcare provider if you have liver conditions.
  • 3.AVOID combining with strong cholinergic or glutamatergic compounds without supervision.
  • 4.NEVER store in a hot, moist environment; keep it in a cool, dry place.
  • 5.DON'T take it late in the evening to avoid sleep disruption.

Who Should NOT Use

  • Pregnant or breastfeeding women
  • Individuals with liver conditions

Use Contexts

Different purposes have different protocols, dosing, and considerations

⚡Recreational

Cognitive enhancement and neuroprotection

moderate evidence

Used by individuals seeking to improve memory, learning, and focus, especially in competitive settings or for neuroprotection.

Evidence: Based on small trials and anecdotal reports from users and forums.

The following are ranges reported in published literature and community discussions. These are NOT recommendations or medical advice.

Reported Range
10-30 mg
Reported Frequency
once daily
Reported Cycle
4-8 weeks
Reported Route
Subcutaneous

Timing: Morning or early afternoon

Notes: Avoid late evening doses to prevent sleep disturbances.

Community-Reported Protocols

Not recommendations: The following protocols are compiled from online communities and published literature. Pepbase does not endorse, recommend, or verify these protocols. They are provided for informational purposes only. Individual responses vary significantly. Consult a licensed medical professional before any use.

Reported GoalReported DoseReported FrequencyReported Route
Cognitive enhancement (beginner)10mg1-2 times dailyOral (sublingual or swallowed)
Intensive cognitive enhancement20-30mg2-3 times dailyOral

Pharmacokinetics

Half-Life
5-10 minutes
Time to Peak
7 minutes
Clearance
Duration 3-5 hours

Reported Side Effects

This is not a complete list. Other side effects may occur.

Common
Headachescommon (1-10%)
Sleep disturbancesreported (frequency unknown)
Irritabilityuncommon (0.1-1%)
Serious / Rare
  • Neurotoxicity concerns
Injection-Specific Warnings
  • Avoid combining with other strong cholinergic compounds.

Storage

Temperature
Room temperature
Reconstituted
Store in a cool, dry place
Shelf Life
Monitor for degradation signs
Light Sensitive
Yes - protect from light

Harm Reduction Information

Quality Concerns

  • Contamination from unregulated sources
  • Degraded product if improperly stored

Safety Tips

  • Use a choline source to reduce headaches
  • Start with a low dose to assess tolerance
  • Store in a cool, dry place away from sunlight

Warning Signs to Stop

  • Persistent headache
  • Severe irritability
  • Sleep disruption

Seek Medical Help Immediately If

  • Muscle spasms
  • Severe mood disturbances

Frequently Asked Questions

Common questions about Omberacetam (Noopept)

How long until I see effects?

Omberacetam typically shows effects within 20 to 60 minutes, with peak absorption around 2 hours.

What time of day should I take it?

For best results, Omberacetam should be taken in the morning or early afternoon to avoid sleep disruption.

How can I minimize side effects?

Pairing Omberacetam with a choline source, such as Alpha-GPC, can help minimize headaches.

Does tolerance develop?

Tolerance to Omberacetam may develop; it's recommended to cycle with breaks of 2-4 weeks after 4-8 weeks of use.

How should I store it?

Store Omberacetam at room temperature, away from moisture and direct sunlight.

Do I need to cycle it?

Yes, cycle Omberacetam for 4-8 weeks on followed by a 2-4 week break to maintain effectiveness.

Reported Combinations

Compounds reported to be used alongside Omberacetam (Noopept) in community discussions

recreational

Semax

Synergistic neuroprotective effects.

recreational

Choline Sources

Prevents headaches, enhances cognitive benefits.

recreational

Dihexa

Potential synergistic effects on memory and learning.

Reported Interactions

Interactions reported in literature and community discussions.

Cholineminor

Often combined to prevent headaches.

Piracetammoderate

Potential for increased side effects due to stacking similar compounds.

Alcoholmoderate

May enhance sedative effects.

Reconstitution Calculator

mL
U100 insulin syringe01020304050607080901001mL

100 units = 1 mL

Safety Tips

  • Always consult a licensed medical professional for dosing and reconstitution instructions.
  • Always double check your units. Mixing up mg and mcg can be very dangerous.
  • Make sure to select your syringe type. U-100 and U-50 syringes have different units.
  • Ensure you're not adding more BAC than your vial can hold. Most vials have maximum capacities listed.

This calculator is for informational and educational purposes only. It does not provide medical advice, dosing recommendations, or safety determinations. Reference ranges shown are compiled from publicly available sources and are not a substitute for guidance from a licensed healthcare professional.

Explore More Research

Browse our database of peptide research information compiled from published literature and community sources.

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Citations

Last updated: October 6, 2023

Important Disclaimer

AI-Generated Content Notice

The information on this page has been compiled using artificial intelligence (AI) and large language model (LLM) technology from multiple sources including published literature, online communities, and public databases. This content may contain errors, inaccuracies, outdated information, or omissions. We make no guarantees regarding the accuracy, completeness, or reliability of any information presented. You are solely responsible for independently verifying any information before relying on it.

Not Medical Advice

Nothing on this website constitutes medical advice, diagnosis, or treatment recommendations. The information provided is for educational and harm-reduction purposes only. We do not provide individualized dosing guidance or treatment recommendations. Protocols and dosing information shown represent reports from community discussions and published literature—they are not endorsements or recommendations. Always consult with a licensed healthcare professional before making any health-related decisions.

No Endorsement of Use

Pepbase does not endorse, encourage, or recommend the use of any peptide or substance discussed on this website. Many compounds discussed are not approved for human use by the FDA or other regulatory agencies. Some substances may be illegal to possess, sell, or use in your jurisdiction. We do not facilitate or encourage the procurement, distribution, or use of controlled or prescription-only substances. Users are solely responsible for understanding and complying with all applicable laws in their jurisdiction.

Calculators and Tools

Any calculators, estimators, or tools provided on this website are for informational purposes only and produce estimates that may be inaccurate. Errors in calculations can result in serious harm. You are solely responsible for verifying all calculations independently. These tools do not account for individual factors that may affect dosing and should never be relied upon as a substitute for professional medical guidance.

Assumption of Risk

By using this website, you acknowledge that you understand the risks associated with using unregulated substances and that you assume full responsibility for your own health decisions. Pepbase, its creators, contributors, and affiliates disclaim all liability for any harm, injury, or damages arising from the use or misuse of information on this website. Use of any information on this site is entirely at your own risk.

If you are experiencing a medical emergency, call emergency services immediately. If you have questions about medications or supplements, consult a licensed pharmacist or physician.