⭐Popular

Selank

Also known as: Selanc, TP-7

CognitiveHealthPerformance
Not FDA Approved

Primary recreational use: Anxiolytic and cognitive enhancement

What is Selank?

Selank is a synthetic heptapeptide analog of tuftsin, developed by the Russian Academy of Sciences for its anxiolytic and nootropic effects. It is primarily used to reduce anxiety and enhance cognitive function without the side effects of traditional benzodiazepines. While approved in Russia, it remains unapproved by the FDA in the United States. Concerns focus on the lack of extensive safety data and potential immunogenic risks.

Primary Benefits

Reduces anxiety. Enhances cognitive function. Modulates immune response.

How It Works

Selank modulates the expression of BDNF, influences serotonin and dopamine metabolism, and affects the GABAergic system. It also exhibits immunomodulatory properties through interactions with the GABA-A receptors, enhancing neuroplasticity and stress resilience.

Safety Tips

Precautions reported in community discussions and literature. This is not a complete list.

  • 1.DON'T start with a high dose - begin with 250mcg to assess tolerance
  • 2.DON'T share vials or needles to avoid infections
  • 3.DON'T use if pregnant or breastfeeding
  • 4.NEVER freeze reconstituted solution
  • 5.DON'T exceed recommended cycle duration of 2-8 weeks
  • 6.AVOID using with alcohol due to potential sedation
  • 7.DON'T inject directly into powder when reconstituting
  • 8.NEVER shake the vial vigorously after reconstitution

Who Should NOT Use

  • Pregnancy
  • Breastfeeding
  • Active cancer

Use Contexts

Different purposes have different protocols, dosing, and considerations

✓Approved Medical

Generalized Anxiety Disorder

strong evidence

Approved in Russia for use in treating generalized anxiety disorder and neurasthenia, demonstrating anxiolytic effects comparable to benzodiazepines without sedation.

Evidence: Approved in Russia after multiple clinical trials demonstrating significant anxiolytic effects in patients with generalized anxiety disorder.

The following are ranges reported in published literature and community discussions. These are NOT recommendations or medical advice.

Reported Range
250-500 mcg
Reported Frequency
once daily
Reported Cycle
2-8 weeks
Reported Route
Subcutaneous

Timing: Morning

Notes: The clinical use is highly regulated with specific dosing protocols in Russia.

Community-Reported Protocols

Not recommendations: The following protocols are compiled from online communities and published literature. Pepbase does not endorse, recommend, or verify these protocols. They are provided for informational purposes only. Individual responses vary significantly. Consult a licensed medical professional before any use.

Reported GoalReported DoseReported FrequencyReported Route
General anxiety relief250mcgonce dailySubcutaneous injection

Pharmacokinetics

Half-Life
3 min
Time to Peak
20 min
Clearance
~15 min

Reported Side Effects

This is not a complete list. Other side effects may occur.

Common
Nasal irritationcommon (1-10%)
Headachecommon (1-10%)
Nauseacommon (1-10%)
Injection-Specific Warnings
  • Use sterile technique to prevent infection

Storage

Temperature
2-8°C
Reconstituted
Use within 30 days
Shelf Life
Store indefinitely if lyophilized
Light Sensitive
Yes - protect from light
⚡Recreational

Cognitive enhancement

limited evidence

Used in biohacking communities for its nootropic effects, aiming to improve cognitive function and stress resilience.

Evidence: Community reports and limited studies indicate improvement in cognitive functions; however, lacks robust clinical evidence outside of Russia.

The following are ranges reported in published literature and community discussions. These are NOT recommendations or medical advice.

Reported Range
250-500 mcg
Reported Frequency
once daily
Reported Cycle
2-8 weeks
Reported Route
Subcutaneous, Intramuscular

Timing: Morning

Notes: User-stacked with other nootropics like Semax.

Community-Reported Protocols

Not recommendations: The following protocols are compiled from online communities and published literature. Pepbase does not endorse, recommend, or verify these protocols. They are provided for informational purposes only. Individual responses vary significantly. Consult a licensed medical professional before any use.

Reported GoalReported DoseReported FrequencyReported Route
Cognitive enhancement250-350mcgonce dailySubcutaneous injection

Pharmacokinetics

Half-Life
3 min
Time to Peak
20 min
Clearance
~15 min

Reported Side Effects

This is not a complete list. Other side effects may occur.

Common
Fatiguereported (frequency unknown)
Non-sedative and non-addictivereported (frequency unknown)
Injection-Specific Warnings
  • Must be stored properly to maintain potency

Storage

Temperature
2-8°C
Reconstituted
Use within 30 days
Shelf Life
Store indefinitely if lyophilized
Light Sensitive
Yes - protect from light

Harm Reduction Information

Quality Concerns

  • Potential contamination from unregulated sources
  • Improper reconstitution can lead to degradation

Safety Tips

  • Use sterile saline for reconstitution
  • Refrigerate immediately after reconstitution
  • Label vial with reconstitution date

Warning Signs to Stop

  • Persistent headache or dizziness
  • Unexplained fatigue
  • Severe nasal irritation

Seek Medical Help Immediately If

  • Severe allergic reaction
  • Difficulty breathing

Frequently Asked Questions

Common questions about Selank

How long until I see effects?

Selank typically provides anxiety relief within 30-60 minutes and cognitive enhancements within 1-3 days.

What time of day should I take it?

It is best to use Selank in the morning for cognitive benefits and during the day as needed for anxiety control.

How can I minimize side effects?

To minimize side effects like nasal irritation when using Selank intranasally, use sterile saline for reconstitution and handle carefully.

Does tolerance develop?

Selank does not typically lead to tolerance, making it a safer alternative to other anxiolytics like benzodiazepines.

How should I store it?

Store Selank at 2-8°C in the refrigerator and use reconstituted solution within 30 days, protected from light.

Do I need to cycle it?

Selank can be cycled with a 2-8 week on, followed by 1-2 weeks off for optimal effectiveness.

Can I combine it with other peptides?

Selank may be stacked with Semax for cognitive enhancement, but it's crucial to monitor for interactions.

Reported Combinations

Compounds reported to be used alongside Selank in community discussions

recreational

Semax

Combining can enhance cognitive effects through synergistic pathways.

recreational

Noopept

May provide enhanced cognitive benefits when used together.

investigational

BPC-157

Combines well for immune modulation and systemic healing.

Reported Interactions

Interactions reported in literature and community discussions.

Benzodiazepinesmoderate

May enhance effects of benzodiazepines.

Alcoholmajor

Avoid combination due to potential sedation.

SSRI Antidepressantsmoderate

Monitor combination as it may alter effects.

Reconstitution Calculator

mL
U100 insulin syringe01020304050607080901001mL

100 units = 1 mL

Safety Tips

  • Always consult a licensed medical professional for dosing and reconstitution instructions.
  • Always double check your units. Mixing up mg and mcg can be very dangerous.
  • Make sure to select your syringe type. U-100 and U-50 syringes have different units.
  • Ensure you're not adding more BAC than your vial can hold. Most vials have maximum capacities listed.

This calculator is for informational and educational purposes only. It does not provide medical advice, dosing recommendations, or safety determinations. Reference ranges shown are compiled from publicly available sources and are not a substitute for guidance from a licensed healthcare professional.

Explore More Research

Browse our database of peptide research information compiled from published literature and community sources.

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Citations

Last updated: October 5, 2023

Important Disclaimer

AI-Generated Content Notice

The information on this page has been compiled using artificial intelligence (AI) and large language model (LLM) technology from multiple sources including published literature, online communities, and public databases. This content may contain errors, inaccuracies, outdated information, or omissions. We make no guarantees regarding the accuracy, completeness, or reliability of any information presented. You are solely responsible for independently verifying any information before relying on it.

Not Medical Advice

Nothing on this website constitutes medical advice, diagnosis, or treatment recommendations. The information provided is for educational and harm-reduction purposes only. We do not provide individualized dosing guidance or treatment recommendations. Protocols and dosing information shown represent reports from community discussions and published literature—they are not endorsements or recommendations. Always consult with a licensed healthcare professional before making any health-related decisions.

No Endorsement of Use

Pepbase does not endorse, encourage, or recommend the use of any peptide or substance discussed on this website. Many compounds discussed are not approved for human use by the FDA or other regulatory agencies. Some substances may be illegal to possess, sell, or use in your jurisdiction. We do not facilitate or encourage the procurement, distribution, or use of controlled or prescription-only substances. Users are solely responsible for understanding and complying with all applicable laws in their jurisdiction.

Calculators and Tools

Any calculators, estimators, or tools provided on this website are for informational purposes only and produce estimates that may be inaccurate. Errors in calculations can result in serious harm. You are solely responsible for verifying all calculations independently. These tools do not account for individual factors that may affect dosing and should never be relied upon as a substitute for professional medical guidance.

Assumption of Risk

By using this website, you acknowledge that you understand the risks associated with using unregulated substances and that you assume full responsibility for your own health decisions. Pepbase, its creators, contributors, and affiliates disclaim all liability for any harm, injury, or damages arising from the use or misuse of information on this website. Use of any information on this site is entirely at your own risk.

If you are experiencing a medical emergency, call emergency services immediately. If you have questions about medications or supplements, consult a licensed pharmacist or physician.